Chief executives of a handful of pharmaceutical and drug distribution companies were negotiating Friday with government attorneys to see if they can reach a settlement ahead of the first federal trial over the nation's opioid crisis.

The opioid crisis cost the U.S. economy $631 billion from 2015 through last year — and it may keep getting more expensive, according to a study released by the Society of Actuaries.

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HARTFORD, Conn. (AP) — The weather was calm and clear at the time of a deadly B-17 crash at a Connecticut airport, and tests on the airplane's fuel did not turn up any sign of debris or contamination, federal investigators said Tuesday.

LOS ANGELES — An aggressive wildfire in Southern California seared its way through dry vegetation Friday and spread quickly, destroying more than a dozen homes as tens of thousands of residents were ordered to get out of its way, authorities said.

WASHINGTON (AP) — The Supreme Court agreed Friday to plunge into the abortion debate in the midst of the 2020 presidential campaign, taking on a Louisiana case that could reveal how willing the more conservative court is to chip away at abortion rights.

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WINDSOR LOCKS, Conn. (AP) — A World War II-era B-17 bomber carrying 13 people crashed and burned at the Hartford airport in an aborted takeoff attempt Wednesday, killing an undetermined number of those aboard, authorities said.

FORT LAUDERDALE, Fla. (AP) — Prosecutors have appealed a judge’s ruling throwing out video evidence that allegedly shows New England Patriots owner Robert Kraft paying for sex at a Florida massage parlor.

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WINDSOR LOCKS, Conn. (AP) — A World War II-era bomber plane crashed Wednesday just outside New England's second-busiest airport, and a fire-and-rescue operation was underway, official said.

UNITED NATIONS — Palestinian President Mahmoud Abbas took to the world stage on Thursday to slam the United States for “depriving the peace process of any credibility” and undermining prospects for a two-state solution to the decades-old Israeli-Palestinian conflict.

WASHINGTON — The explosive details of a whistleblower's complaint against President Donald Trump provided Democrats on Thursday with a roadmap for their impeachment inquiry but left Republicans straining under the most serious test yet of their alliance with the White House.

The U.S. House on Wednesday passed a bill that would protect banks working with state-legal marijuana companies from federal regulatory penalties, allowing the largely cash-only legal marijuana to move towards other payment options.

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WASHINGTON (AP) — The whistleblower at the center of Congress' impeachment inquiry alleged that President Donald Trump abused the power of his office to "solicit interference from a foreign country" in next year's U.S. election. The White House then tried to "lock down" the information to co…

WASHINGTON — Members of Congress on Wednesday were able for the first time to review the secret whistleblower complaint involving President Donald Trump that has triggered a coordinated impeachment effort in the House.

Democratic presidential candidate Beto O'Rourke's recent vow to take away people's AR-15 and AK-47 rifles raised one big question: How is it possible to round up the millions of such guns that exist in the United States?

NEW YORK — A New Jersey man who allegedly photographed or recorded video of landmarks including the Statue of Liberty, the White House and Boston’s Fenway Park as potential terrorism targets in the early to mid-2000s has been charged with terror offenses by authorities who say he was working…

BOSTON — "Desperate Housewives" star Felicity Huffman was sentenced Friday to 14 days in prison for paying $15,000 to rig her daughter's SAT scores, tearfully apologizing to the teenager for not trusting her to get into college on her own.

BOSTON — Talks between state attorneys general and Purdue Pharma over a possible $12 billion settlement to resolve thousands of lawsuits brought against the opioid manufacturer have stalled, in part because Massachusetts Attorney General Maura Healey is not on board, according to a national …

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NEW YORK (AP) — Walmart has won praise from gun control advocates for its decision to discontinue sales of certain gun ammunition and request that customers no longer openly carry firearms in its stores. But whether the moves will translate into fewer guns on the street remains an open question.

COATZACOALCOS, Mexico — Mexico’s drug war appears to be back — and it may be worse this time around than in the bloody years of the government’s 2006-2012 offensive against drug cartels.

MIAMI — An increasingly alarming Hurricane Dorian menaced a corridor of some 10 million people — and put Walt Disney World and President Donald Trump's Mar-a-Lago resort in the crosshairs — as it steamed toward Florida on Friday with the potential to become the most powerful storm to hit the…

WASHINGTON — Move over, Nancy Pelosi. Rep. Alexandria Ocasio-Cortez and the "squad" of freshmen women of color are emerging as new stars of Republican attacks against Democrats running for Congress.

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